名古屋大学“预防感染症”最新研究成果:确定微生物种类,只需一个水泵

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Text in the picture: nanowires, microbes, DNA

Dumpling dumplings have something to say:

Nagoya University in Japan has developed a technology that "the microorganisms can be easily broken by washing the microorganisms with a water pump, and specific microbial species".

Dumpling dumplings feel that this research topic is very interesting and shared with you~

The research was carried out by Professor Masahiro Masahiro of the Graduate School of Engineering, Nagoya University, and Associate Professor Anji Takashi, and Professor Yanagida of the Institute of Materials Chemistry of Kyushu University and Professor Kawasaki Chiji of the Institute of Industrial Science of Osaka University.

The research results are published on the website of the American Chemical Society magazine《ACS Nano》. If your profession is related to medicine, if you are interested, it is recommended to search for it~

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The first line is from left to right: introduction of microbial suspension, microbial disruption, and DNA extraction. The second line is from left to right: adsorption, entanglement, cell deformation, breakage

Microorganisms have cell walls, so they are more resistant to external stimuli than animal cells. In general, the type of microorganism can be determined by investigating the DNA inside the microorganism.

In the past, because there was no technology to efficiently and easily break down microorganisms, specific microorganisms were prepared by experts with special agents. In other words, it is just a matter of how to efficiently and easily break down microorganisms and investigate the DNA inside the microorganisms.

This time, the research team led by Professor Ma Xing Jiaxin re-developed the microbial disruption method that activates the characteristics of nanorods (nanowires): the microorganisms are efficiently and easily pulverized by flushing the solution in which the microorganisms are dispersed by a water pump. It can be said that it is a subversive innovation in the past microbial disruption technology!

The most amazing thing is that this technology can also easily handle yeast that is harder to break than coliforms and subtilis!

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纳米线:一维棒状纳米结构,由10至100纳米组成。

大肠杆菌:环境中存在的主要细菌(细菌)之一。

枯草芽孢杆菌:土壤和植物中常见的细菌(细菌)之一。

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在电子显微镜下观察纳米线损坏的酵母

此外,通过与“纳米线断裂后能够放大微生物的DNA装置”的组合,名古屋大学还开发了一种通过观察眼睛的颜色变化来锁定微生物的技术。相关人员只需要收集含有微生物的溶液,并检查混合物。在安装药物并打开开关后,可以检查家中是否有“O-157大肠杆菌”样细菌等。

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纳米线装置和DNA扩增装置的组合

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检测到大肠杆菌(200)。当存在大肠杆菌时,溶剂从橙色变为绿色。

名古屋大学的研究小组表示,该技术可以轻松检测出危险的微生物。通过采用特定的微生物方法,可以有效地防止由微生物引起的感染。这是对医学的重大贡献

新闻参考:名古屋大学网络

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